At the JPMorgan Healthcare Conference in San Francisco, executives from Forge Therapeutics seek the backing they need to move forward. The sun is nearly down in San Francisco and Zak Zimmerman and David Puerta are worried about arriving late for their final meeting on a long day. It is the first day of the JPMorgan Healthcare Conference, and the men, leaders of the biotech startup Forge Therapeutics, have been up since long before dawn.